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The Bible repeatedly mentions the bitterness of soul (1 Samuel 1:10; Job 3:20; Job 7:11; Job 10:1; Job 21:25; Isaiah 38:15). Job testified to speaking in the bitterness of his soul—weary of his life (Job 10:1). Hannah “was in bitterness of soul” (1 Samuel 1:10) when she spoke to the Lord concerning her desire to birth a son. Interestingly, the Book of Job contains the majority of references to bitterness of soul. It is hard to imagine any mortal man enduring more afflictions of the soul than Job. He was afflicted so deeply, he cursed the day that he was born (Job 3:1). Eventually, his bitterness of soul won out and caused him to sin against the Lord. Hannah, however, spoke to the Lord in bitterness of soul and God rewarded her for her faithfulness.
Likely, no mere mortal endured more difficulty over a short period of time than did Job. Job suffered several awful trials with most of them coming simultaneously. Perhaps Job should not be remembered so much for the trials, but for how he handled those trials. When Job received the news that his children had perished, he said, “Naked came I out of my mother's womb, and naked shall I return thither: the LORD gave, and the LORD hath taken away; blessed be the name of the LORD” (Job 1:21). The verse which follows Job’s statement conveys volumes, “In all this Job sinned not, nor charged God foolishly.” Job’s endurance of such trials led the Lord to point to Job as an outstanding example of patience (James 5:11).